Search on: EARLY GROWTH RESPONSE PROTEIN 2 
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Descriptor English:   Early Growth Response Protein 2 
Descriptor Spanish:   Proteína 2 de la Respuesta de Crecimiento Precoz 
Descriptor Portuguese:   Proteína 2 de Resposta de Crescimento Precoce 
Tree Number:   D12.776.260.158.750
D12.776.460.525.750
D12.776.930.313.750
Definition English:   An early growth response transcription factor that controls the formation of the MYELIN SHEATH around peripheral AXONS by SCHWANN CELLS. Mutations in EGR2 transcription factor have been associated with HEREDITARY MOTOR AND SENSORY NEUROPATHIES such as CHARCOT-MARIE-TOOTH DISEASE. 
See Related English:   Charcot-Marie-Tooth Disease
 
History Note English:   2006(1988) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50983 
Unique Identifier:   D051767 

Occurrence in VHL:
 

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